Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated that not all subunits of eIF3 are essential for the initiation of translation, suggesting that some subunits may se...

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Bibliographic Details
Main Authors: Cattie, Douglas John, Richardson, Claire Elissa, Reddy, Kirthi C., Ness-Cohn, Elan M., Droste, Rita, Thompson, Mary Katherine, Gilbert, Wendy, Kim, Dennis H.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2017
Online Access:http://hdl.handle.net/1721.1/107842
https://orcid.org/0000-0002-8840-3802
https://orcid.org/0000-0001-8281-6916
https://orcid.org/0000-0003-2807-9657
https://orcid.org/0000-0002-4109-5152

Internet

http://hdl.handle.net/1721.1/107842
https://orcid.org/0000-0002-8840-3802
https://orcid.org/0000-0001-8281-6916
https://orcid.org/0000-0003-2807-9657
https://orcid.org/0000-0002-4109-5152

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