Parent-of-Origin DNA Methylation Dynamics during Mouse Development

Parent-specific differentially methylated regions (DMRs) are established during gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic expression of imprinted genes is essential for development, suggesting that imprints are faithfully maintained in embryos and adults....

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Bibliographic Details
Main Authors: Stelzer, Yonatan, Wu, Hao, Song, Yuelin, Shivalila, Chikdu S., Markoulaki, Styliani, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/107925
https://orcid.org/0000-0001-5466-859X