Interleukins 7 and 15 Maintain Human T Cell Proliferative Capacity through STAT5 Signaling
T lymphocytes require signals from self-peptides and cytokines, most notably interleukins 7 and 15 (IL-7, IL-15), for survival. While mouse T cells die rapidly if IL-7 or IL-15 is withdrawn, human T cells can survive prolonged withdrawal of IL-7 and IL-15. Here we show that IL-7 and IL-15 are requir...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2017
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| Online Access: | http://hdl.handle.net/1721.1/107955 https://orcid.org/0000-0001-9816-2187 https://orcid.org/0000-0002-5687-6154 |