Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel

The impact of topical antiretrovirals for pre-exposure prophylaxis on humoral responses following HIV infection is unknown. Using a binding antibody multiplex assay, we investigated HIV-specific IgG and IgA responses to envelope glycoproteins, p24 Gag and p66, in the genital tract (GT) and plasma fo...

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Bibliographic Details
Main Authors: Archary, D, Seaton, K E, Passmore, J S, Werner, L, Deal, A, Yates, N L, Bergin, P, Liebenberg, L J, Samsunder, N, Mureithi, M W, Altfeld, M, Garrett, N, Abdool Karim, Q, Abdool Karim, S S, Morris, L, Tomaras, G D, Dunphy, Laura J., Arnold, Kelly Benedict, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/107971