Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics

Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics

Antibodies are currently the fastest-growing class of therapeutics. Although naked antibodies have proven valuable as pharmaceutical agents, they have some limitations, such as low tissue penetration and a long circulatory half-life. They have been conjugated to toxic payloads, PEGs, or radioisotope...

Full description

Bibliographic Details
Main Authors: Rashidian, Mohammad, Wang, Lu, Edens, Jerre G., Jacobsen, Johanne T., Hossain, Intekhab, Wang, Qifan, Victora, Gabriel D., Vasdev, Neil, Liang, Steven H., Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/107992
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/107992
https://orcid.org/0000-0002-1090-6071

Similar Items