Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

While the catalog of mammalian transcripts and their expression levels in different cell types and disease states is rapidly expanding, our understanding of transcript function lags behind. We present a robust technology enabling systematic investigation of the cellular consequences of repressing or...

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Bibliographic Details
Main Authors: Gilbert, Luke A., Horlbeck, Max A., Adamson, Britt, Villalta, Jacqueline E., Chen, Yuwen, Whitehead, Evan H., Guimaraes, Carla, Panning, Barbara, Bassik, Michael C., Qi, Lei S., Kampmann, Martin, Weissman, Jonathan S., Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/108008
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/108008
https://orcid.org/0000-0002-1090-6071

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