'Deadman' and 'Passcode' microbial kill switches for bacterial containment

Biocontainment systems that couple environmental sensing with circuit-based control of cell viability could be used to prevent escape of genetically modified microbes into the environment. Here we present two engineered safeguard systems known as the 'Deadman' and 'Passcode' kill...

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Bibliographic Details
Main Authors: Bashor, Caleb, Collins, James J., Chan, Clement T. Y., Lee, Jeongwook, Cameron, Douglas
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108106
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0003-0705-0177