'Deadman' and 'Passcode' microbial kill switches for bacterial containment
Biocontainment systems that couple environmental sensing with circuit-based control of cell viability could be used to prevent escape of genetically modified microbes into the environment. Here we present two engineered safeguard systems known as the 'Deadman' and 'Passcode' kill...
Main Authors: | Bashor, Caleb, Collins, James J., Chan, Clement T. Y., Lee, Jeongwook, Cameron, Douglas |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/108106 https://orcid.org/0000-0002-5560-8246 https://orcid.org/0000-0003-0705-0177 |
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