Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

The chirality, or ‘handedness’, of a biologically active molecule can alter its physiological properties. Thus it is routine procedure in the drug discovery and development process to prepare and fully characterize all possible stereoisomers of a drug candidate for biological evaluation. Despite man...

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Bibliographic Details
Main Authors: Buchwald, Stephen Leffler, Shi, Shiliang, Wong, Zackary Leland
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108111
https://orcid.org/0000-0003-3875-4775
https://orcid.org/0000-0002-7917-7620
https://orcid.org/0000-0003-3732-5178