Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

The effectiveness of stem cell therapies has been hampered by cell death and limited control over fate. These problems can be partially circumvented by using macroporous biomaterials that improve the survival of transplanted stem cells and provide molecular cues to direct cell phenotype. Stem cell b...

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Bibliographic Details
Main Authors: Lippens, Evi, Lee, Kangwon, Mehta, Manav, Koshy, Sandeep T., Darnell, Max C., Desai, Rajiv M., Madl, Christopher M., Xu, Maria, Zhao, Xuanhe, Chaudhuri, Ovijit, Verbeke, Catia, Kim, Woo Seob, Alim, Karen, Mammoto, Akiko, Ingber, Donald E., Duda, Georg N., Mooney, David J., Huebsch, Nathaniel David
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108166

Internet

http://hdl.handle.net/1721.1/108166

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