A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic residual cancer in the tumor bed could be used to decrease the risk of a positive surgical margin, reduce rates of reexcision, and tailor adjuvant therapy. We used a protea...

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Bibliographic Details
Main Authors: Whitley, M. J., Cardona, D. M., Lazarides, A. L., Spasojevic, I., Ferrer, J. M., Lee, C.-L., Snuderl, M., Blazer, D. G., Hwang, E. S., Greenup, R. A., Mosca, P. J., Mito, J. K., Cuneo, K. C., Larrier, N. A., OReilly, E. K., Riedel, R. F., Eward, W. C., Strasfeld, D. B., Fukumura, D., Lee, W. D., Kirsch, D. G., Brigman, B. E., Cahill, Joan, Jain, Rakesh J., Griffith, Linda G, Bawendi, Moungi G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/108186
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0003-2220-4365

Internet

http://hdl.handle.net/1721.1/108186
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0003-2220-4365

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