Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides

An HIV vaccine capable of inducing high and durable levels of broadly neutralizing antibodies has thus far proven elusive. A promising antigen is the membrane-proximal external region (MPER) from gp41, a segment of the viral envelope recognized by a number of broadly neutralizing antibodies. Though...

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Bibliographic Details
Main Authors: Kim, Mikyung, Reinherz, Ellis L., Abraham, Wuhbet, Hanson, Melissa Catherine, Liu, Haipeng, Szeto, Gregory, Irvine, Darrell J, Chen, Stephanie H., Crespo, Monica P.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/108190
https://orcid.org/0000-0002-4267-237X
https://orcid.org/0000-0001-7604-1333