Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression

Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression

Chronic mucosal inflammation is associated with a greater risk of gastric cancer (GC) and, therefore, requires tight control by suppressive counter mechanisms. Gastrokine-2 (GKN2) belongs to a family of secreted proteins expressed within normal gastric mucosal cells. GKN2 expression is frequently lo...

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Bibliographic Details
Main Authors: Menheniott, Trevelyan R., O’Connor, Louise, Chionh, Yok Teng, Däbritz, Jan, Scurr, Michelle, Rollo, Benjamin N., Ng, Garrett Z., Jacobs, Shelley, Catubig, Angelique, Kurklu, Bayzar, Mercer, Stephen, Minamoto, Toshinari, Ong, David E., Ferrero, Richard L., Wang, Timothy C., Sutton, Philip, Judd, Louise M., Giraud, Andrew S., Fox, James G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Clinical Investigation 2017
Online Access:http://hdl.handle.net/1721.1/108195
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/108195
https://orcid.org/0000-0001-9307-6116

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