Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

Activation of immune cells (but not B cells) with lectins is widely known. We used the structurally defined interaction between influenza hemagglutinin (HA) and its cell surface receptor sialic acid (SA) to identify a B cell receptor (BCR) activation modality that proceeded through non-cognate inter...

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Bibliographic Details
Main Authors: Villar, Rina F., Weaver, Grant C., Kanekiyo, Masaru, Wheatley, Adam K., Yassine, Hadi M., Costello, Catherine E., Chandler, Kevin B., McTamney, Patrick. M., Nabel, Gary J., McDermott, Adrian B., Mascola, John R., Lingwood, Daniel, Patel, Jinal, Carr, Steven A
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108346
https://orcid.org/0000-0002-7203-4299