In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line

In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line

To date, the exact targets and mechanism of action of curcumin, a natural product with anti-inflammatory and anti-cancer properties, remain elusive. Here we synthesized a cell permeable curcumin probe (Cur-P) with an alkyne moiety, which can be tagged with biotin for affinity enrichment, or with a f...

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Bibliographic Details
Main Authors: Wang, Jigang, Zhang, Jianbin, Zhang, Chong-Jing, Wong, Yin Kwan, Lim, Teck Kwang, Hua, Zi-Chun, Liu, Bin, Shen, Han-Ming, Lin, Qingsong, Tannenbaum, Steven R
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108372

Internet

http://hdl.handle.net/1721.1/108372

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