Use of [superscript 18]F‑2-Fluorodeoxyglucose to Label Antibody Fragments for Immuno-Positron Emission Tomography of Pancreatic Cancer

Use of [superscript 18]F‑2-Fluorodeoxyglucose to Label Antibody Fragments for Immuno-Positron Emission Tomography of Pancreatic Cancer

We generated [superscript 18]F-labeled antibody fragments for positron emission tomography (PET) imaging using a sortase-mediated reaction to install a trans-cyclooctene-functionalized short peptide onto proteins of interest, followed by reaction with a tetrazine-labeled-[superscript 18]F-2-deoxyflu...

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Bibliographic Details
Main Authors: Keliher, Edmund J., Dougan, Michael, Cavallari, Marco, Wojtkiewicz, Gregory R., Jacobsen, Johanne T., Edens, Jerre G., Tas, Jeroen M. J., Victora, Gabriel, Weissleder, Ralph, Rashidian, Mohammad, Juras, Patrick K., Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/108397
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/108397
https://orcid.org/0000-0002-1090-6071

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