Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers

Many microbial communities are characterized by high genetic diversity. 16S ribosomal RNA sequencing can determine community members, and metagenomics can determine the functional diversity, but resolving the functional role of individual cells in high throughput remains an unsolved challenge. Here,...

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Bibliographic Details
Main Authors: Guo, Mira T, Briggs, Adrian W, A Weitz, David, Pitkänen, Leena K, Vigneault, Francois, Virta, Marko PJuhani, Spencer, Sarah J., Tamminen, Manu V., Preheim, Sarah P., Brito, Ilana Lauren
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108419
https://orcid.org/0000-0002-2744-8994
https://orcid.org/0000-0001-5891-7653