Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
Genome-wide association studies (GWAS) have identified numerous genetic variants associated with complex diseases, but mechanistic insights are impeded by a lack of understanding of how specific risk variants functionally contribute to the underlying pathogenesis. It has been proposed that cis-actin...
Main Authors: | Soldner, Frank, Stelzer, Yonatan, Abraham, Brian J., Latourelle, Jeanne C., Barrasa, M. Inmaculada, Goldmann, Johanna, Myers, Richard H., Jaenisch, Rudolf, Shivalila, Chikdu Shakti, Young, Richard A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/108430 https://orcid.org/0000-0001-8855-8647 https://orcid.org/0000-0002-2905-0306 |
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