Transcription factor trapping by RNA in gene regulatory elements

Transcription factor trapping by RNA in gene regulatory elements

Transcription factors (TFs) bind specific sequences in promoter-proximal and -distal DNA elements to regulate gene transcription. RNA is transcribed from both of these DNA elements, and some DNA binding TFs bind RNA. Hence, RNA transcribed from regulatory elements may contribute to stable TF occupan...

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Bibliographic Details
Main Authors: Sigova, A. A., Abraham, B. J., Ji, X., Molinie, B., Hannett, N. M., Guo, Y. E., Giallourakis, C. C., Jangi, Mohini Rohit, Sharp, Phillip A., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/108470
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/108470
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0001-8855-8647

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