Transcription factor trapping by RNA in gene regulatory elements
Transcription factors (TFs) bind specific sequences in promoter-proximal and -distal DNA elements to regulate gene transcription. RNA is transcribed from both of these DNA elements, and some DNA binding TFs bind RNA. Hence, RNA transcribed from regulatory elements may contribute to stable TF occupan...
Main Authors: | Sigova, A. A., Abraham, B. J., Ji, X., Molinie, B., Hannett, N. M., Guo, Y. E., Giallourakis, C. C., Jangi, Mohini Rohit, Sharp, Phillip A., Young, Richard A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2017
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Online Access: | http://hdl.handle.net/1721.1/108470 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0001-8855-8647 |
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