Replication Fork Progression during Re-replication Requires the DNA Damage Checkpoint and Double-Strand Break Repair
Replication origins are under tight regulation to ensure activation occurs only once per cell cycle. Origin re-firing in a single S phase leads to the generation of DNA double-strand breaks (DSBs) and activation of the DNA damage checkpoint. If the checkpoint is blocked, cells enter mitosis with par...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2017
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| Online Access: | http://hdl.handle.net/1721.1/108471 https://orcid.org/0000-0002-7934-111X https://orcid.org/0000-0003-4643-2282 |