Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis

Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis

Translesion synthesis (TLS) is a mutagenic branch of cellular DNA damage tolerance that enables bypass replication over DNA lesions carried out by specialized low-fidelity DNA polymerases. The replicative bypass of most types of DNA damage is performed in a two-step process of Rev1/Polζ-dependent TL...

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Bibliographic Details
Main Authors: Pustovalova, Yulia, Magalhães, Mariana T. Q., Rizzo, Alessandro A., Korza, George, Korzhnev, Dmitry M., D'Souza, Sanjay Victor, Walker, Graham C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/108560
https://orcid.org/0000-0001-7243-8261

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http://hdl.handle.net/1721.1/108560
https://orcid.org/0000-0001-7243-8261

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