RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

During morphogenesis, contraction of the actomyosin cytoskeleton within individual cells drives cell shape changes that fold tissues. Coordination of cytoskeletal contractility is mediated by regulating RhoA GTPase activity. Guanine nucleotide exchange factors (GEFs) activate and GTPase-activating p...

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Bibliographic Details
Main Authors: Mason, Frank M, Xie, Shicong, Vasquez, Claudia G, Martin, Adam C, Tworoger, Michael B.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Rockefeller University Press, The 2017
Online Access:http://hdl.handle.net/1721.1/108604
https://orcid.org/0000-0003-1338-494X
https://orcid.org/0000-0002-3283-3248
https://orcid.org/0000-0002-8987-7508
https://orcid.org/0000-0001-8060-2607

Internet

http://hdl.handle.net/1721.1/108604
https://orcid.org/0000-0003-1338-494X
https://orcid.org/0000-0002-3283-3248
https://orcid.org/0000-0002-8987-7508
https://orcid.org/0000-0001-8060-2607

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