Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis

Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis

Background The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mitochondrial mutation would have occurred in a founding cell and spread...

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Bibliographic Details
Main Authors: Morgenthaler, Stephan, Refinetti, Paulo, Thilly, William G, Ekstrom, Per Olaf
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central 2017
Online Access:http://hdl.handle.net/1721.1/108632
https://orcid.org/0000-0003-2581-6092

Internet

http://hdl.handle.net/1721.1/108632
https://orcid.org/0000-0003-2581-6092

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