The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
Amino acids signal to the mTOR complex I (mTORC1) growth pathway through the Rag GTPases. Multiple distinct complexes regulate the Rags, including GATOR1, a GTPase activating protein (GAP), and GATOR2, a positive regulator of unknown molecular function. Arginine stimulation of cells activates mTORC1...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2017
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| Online Access: | http://hdl.handle.net/1721.1/108635 https://orcid.org/0000-0001-9388-1633 https://orcid.org/0000-0002-9376-3984 https://orcid.org/0000-0003-4642-3706 https://orcid.org/0000-0002-4227-5163 https://orcid.org/0000-0002-1446-7256 |