Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from
Fumarate hydratases (FHs) are essential metabolic enzymes grouped into two classes. Here, we present the crystal structure of a class I FH, the cytosolic FH from Leishmania major, which reveals a previously undiscovered protein fold that coordinates a catalytically essential [4Fe-4S] cluster. Our 2....
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2017
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| Online Access: | http://hdl.handle.net/1721.1/108745 https://orcid.org/0000-0003-3853-115X https://orcid.org/0000-0001-5486-2755 |