Controlling uncertainty in aptamer selection

The search for high-affinity aptamers for targets such as proteins, small molecules, or cancer cells remains a formidable endeavor. Systematic Evolution of Ligands by EXponential Enrichment (SELEX) offers an iterative process to discover these aptamers through evolutionary selection of high-affinity...

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Bibliographic Details
Main Authors: Spill, Fabian, Weinstein, Zohar B., Irani Shemirani, Atena, Ho, Nga, Desai, Darash, Zaman, Muhammad H.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/108794
https://orcid.org/0000-0001-8462-5080