Controlling uncertainty in aptamer selection
The search for high-affinity aptamers for targets such as proteins, small molecules, or cancer cells remains a formidable endeavor. Systematic Evolution of Ligands by EXponential Enrichment (SELEX) offers an iterative process to discover these aptamers through evolutionary selection of high-affinity...
Main Authors: | Spill, Fabian, Weinstein, Zohar B., Irani Shemirani, Atena, Ho, Nga, Desai, Darash, Zaman, Muhammad H. |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2017
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Online Access: | http://hdl.handle.net/1721.1/108794 https://orcid.org/0000-0001-8462-5080 |
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