Optimal immunization cocktails can promote induction of broadly neutralizing Abs against highly mutable pathogens
Strategies to elicit Abs that can neutralize diverse strains of a highly mutable pathogen are likely to result in a potent vaccine. Broadly neutralizing Abs (bnAbs) against HIV have been isolated from patients, proving that the human immune system can evolve them. Using computer simulations and theo...
| Main Authors: | , , , |
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| 格式: | 文件 |
| 语言: | en_US |
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National Academy of Sciences (U.S.)
2017
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| 在线阅读: | http://hdl.handle.net/1721.1/108795 https://orcid.org/0000-0002-1124-6124 https://orcid.org/0000-0002-1112-5912 https://orcid.org/0000-0003-1268-9602 |