Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

Genetically engineered mouse models (GEMMs) of cancer are increasingly being used to assess putative driver mutations identified by large-scale sequencing of human cancer genomes. To accurately interpret experiments that introduce additional mutations, an understanding of the somatic genetic profile...

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书目详细资料
Main Authors: Politi, Katerina, Song, Xiaoling, Pirun, Mono, Kim-Kiselak, Caroline, Platt, James T., Lee, Emily, Hodges, Emily, Rosebrock, Adam P., Bronson, Roderick T., Socci, Nicholas D., Hannon, Gregory J., Varmus, Harold, McFadden, David Glenn, Bhutkar, Arjun, Chen, Frances K., Santiago, Philip M., Jacks, Tyler E.
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
语言:en_US
出版: National Academy of Sciences (U.S.) 2017
在线阅读:http://hdl.handle.net/1721.1/108807
https://orcid.org/0000-0001-5785-8911