Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

Genetically engineered mouse models (GEMMs) of cancer are increasingly being used to assess putative driver mutations identified by large-scale sequencing of human cancer genomes. To accurately interpret experiments that introduce additional mutations, an understanding of the somatic genetic profile...

Повний опис

Бібліографічні деталі
Автори: Politi, Katerina, Song, Xiaoling, Pirun, Mono, Kim-Kiselak, Caroline, Platt, James T., Lee, Emily, Hodges, Emily, Rosebrock, Adam P., Bronson, Roderick T., Socci, Nicholas D., Hannon, Gregory J., Varmus, Harold, McFadden, David Glenn, Bhutkar, Arjun, Chen, Frances K., Santiago, Philip M., Jacks, Tyler E.
Інші автори: Massachusetts Institute of Technology. Department of Biology
Формат: Стаття
Мова:en_US
Опубліковано: National Academy of Sciences (U.S.) 2017
Онлайн доступ:http://hdl.handle.net/1721.1/108807
https://orcid.org/0000-0001-5785-8911

Інтернет

http://hdl.handle.net/1721.1/108807
https://orcid.org/0000-0001-5785-8911

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