A Structure-free Method for Quantifying Conformational Flexibility in proteins

All proteins sample a range of conformations at physiologic temperatures and this inherent flexibility enables them to carry out their prescribed functions. A comprehensive understanding of protein function therefore entails a characterization of protein flexibility. Here we describe a novel approac...

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Bibliographic Details
Main Authors: Arenas, Daniel J., Burger, Virginia, Stultz, Collin M
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108809
https://orcid.org/0000-0002-8612-4797
https://orcid.org/0000-0002-3415-242X