Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

Mammalian DNA methylation plays an essential role in development. To date, only snapshots of different mouse and human cell types have been generated, providing a static view on DNA methylation. To enable monitoring of methylation status as it changes over time, we establish a reporter of genomic me...

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Bibliographic Details
Main Authors: Stelzer, Yonatan, Soldner, Frank, Markoulaki, Styliani, Shivalila, Chikdu Shakti, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/108812
https://orcid.org/0000-0002-2905-0306