Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Genetic variants affecting hematopoiesis can influence commonly measured blood cell traits. To identify factors that affect hematopoiesis, we performed association studies for blood cell traits in the population-based Estonian Biobank using high-coverage whole-genome sequencing (WGS) in 2,284 sample...

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Bibliographic Details
Main Authors: Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Mägi, Reedik, Palta, Priit, Metspalu, Andres, Esko, Tõnu, Zekavat, Seyedeh M., Gabriel, Stacey, Lander, Eric Steven, Kathiresan, Sekar, Sankaran, Vijay G., Hirschhorn, Joel N.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/108856