Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Genetic variants affecting hematopoiesis can influence commonly measured blood cell traits. To identify factors that affect hematopoiesis, we performed association studies for blood cell traits in the population-based Estonian Biobank using high-coverage whole-genome sequencing (WGS) in 2,284 sample...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Mägi, Reedik, Palta, Priit, Metspalu, Andres, Esko, Tõnu, Zekavat, Seyedeh M., Gabriel, Stacey, Lander, Eric Steven, Kathiresan, Sekar, Sankaran, Vijay G., Hirschhorn, Joel N.
Weitere Verfasser: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Artikel
Sprache:en_US
Veröffentlicht: National Academy of Sciences (U.S.) 2017
Online Zugang:http://hdl.handle.net/1721.1/108856

Online

http://hdl.handle.net/1721.1/108856

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