MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

G protein-coupled receptor (GPCR) signalling, including that involving apelin (APLN) and its receptor APLNR, is known to be important in vascular development. How this ligand–receptor pair regulates the downstream signalling cascades in this context remains poorly understood. Here, we show that mice...

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Bibliographic Details
Main Authors: Papangeli, Irinna, Kim, Jongmin, Maier, Inna, Park, Saejeong, Lee, Aram, Kang, Yujung, Tanaka, Keiichiro, Ju, Hyekyung, Kojima, Yoko, Red-Horse, Kristy, Siekmann, Arndt F., Chun, Hyung J., Khan, Omar Fizal, Anderson, Daniel Griffith
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/109190
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0001-5629-4798