5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic spread. Although early stages of invadopodia assembly have been elucidated, little is known about maturation of invadopodia into structures compet...

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Bibliographic Details
Main Authors: Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Siegel, Peter M., Park, Morag, Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Rockefeller University Press 2017
Online Access:http://hdl.handle.net/1721.1/109203
https://orcid.org/0000-0003-3214-4554

Internet

http://hdl.handle.net/1721.1/109203
https://orcid.org/0000-0003-3214-4554

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