Microfluidic neurite guidance to study structure-function relationships in topologically-complex population-based neural networks

The central nervous system is a dense, layered, 3D interconnected network of populations of neurons, and thus recapitulating that complexity for in vitro CNS models requires methods that can create defined topologically-complex neuronal networks. Several three-dimensional patterning approaches have...

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Bibliographic Details
Main Authors: Honegger, Thibault, Thielen, Moritz Imanuel, Voldman, Joel, Feizi- Khankandi, Soheil, Sanjana, Neville E
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/109255
https://orcid.org/0000-0001-8898-2296
https://orcid.org/0000-0002-0964-0616