Confined crystallization of fenofibrate in nanoporous silica

Producing stable nanocrystals confined to porous excipient media is a desirable way to increase the dissolution rate and improve the bioavailability of poorly water soluble pharmaceuticals. The poorly soluble pharmaceutical fenofibrate was crystallized in controlled pore glass (CPG) of 10 different...

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Bibliographic Details
Main Authors: Dwyer, Leia Mary, Michaelis, Vladimir K., O'Mahony, Marcus, Griffin, Robert Guy, Myerson, Allan S.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2017
Online Access:http://hdl.handle.net/1721.1/109274
https://orcid.org/0000-0002-7596-3595
https://orcid.org/0000-0002-6708-7660
https://orcid.org/0000-0002-7352-5962
https://orcid.org/0000-0003-1589-832X
https://orcid.org/0000-0002-7468-8093