Total synthesis and biochemical characterization of mirror image barnase

In this study we synthesized and characterized mirror image barnase (B. amyloliquefaciens ribonuclease). D-Barnase was identical to L-barnase, when analyzed by liquid chromatography and mass-spectrometry. Proteolysis of the mirror image enzyme revealed that in contrast to its native counterpart, D-b...

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Bibliographic Details
Main Authors: Vinogradov, Alexander Alexandrovich, Evans, Ethan Daniel, Pentelute, Bradley L.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Royal Society of Chemistry, The 2017
Online Access:http://hdl.handle.net/1721.1/109283
https://orcid.org/0000-0002-5508-0963
https://orcid.org/0000-0002-9383-2185