A Bacterial Mutant Library as a Tool to Study the Attack of a Defensin Peptide

Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

Bibliographic Details
Main Authors: Moser, Simone, Chileveru, Haritha reddy, Tomaras, Jill M, Nolan, Elizabeth Marie
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/109285
https://orcid.org/0000-0002-2515-5901
https://orcid.org/0000-0002-6153-8803