A Bacterial Mutant Library as a Tool to Study the Attack of a Defensin Peptide
Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.
Main Authors: | Moser, Simone, Chileveru, Haritha reddy, Tomaras, Jill M, Nolan, Elizabeth Marie |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
Wiley Blackwell
2017
|
Online Access: | http://hdl.handle.net/1721.1/109285 https://orcid.org/0000-0002-2515-5901 https://orcid.org/0000-0002-6153-8803 |
Similar Items
-
Visualizing the attack of bacteria by the antimicrobial peptide human defensin 5
by: Chileveru, Haritha Reddy
Published: (2016) -
Discovery and Characterization of a Disulfide-Locked C[subscript 2]-Symmetric Defensin Peptide
by: Ziarek, Joshua J., et al.
Published: (2017) -
Visualizing Attack of Escherichia coli by the Antimicrobial Peptide Human Defensin 5
by: Chileveru, Haritha Reddy, et al.
Published: (2016) -
Human α-Defensin 6: A Small Peptide That Self-Assembles and Protects the Host by Entangling Microbes
by: Chairatana, Phoom, et al.
Published: (2018) -
Proteolysis triggers self-assembly and unmasks innate immune function of a human α-defensin peptide
by: Chu, Hiutung, et al.
Published: (2016)