Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins
Viral homologs of the anti-apoptotic Bcl-2 proteins are highly diverged from their mammalian counterparts, yet they perform overlapping functions by binding and inhibiting BH3 (Bcl-2 homology 3)-motif-containing proteins. We investigated the BH3 binding properties of the herpesvirus Bcl-2 homologs K...
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Format: | Article |
Language: | en_US |
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Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/109320 https://orcid.org/0000-0003-3749-7092 https://orcid.org/0000-0003-4074-8980 |