Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins

Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins

Viral homologs of the anti-apoptotic Bcl-2 proteins are highly diverged from their mammalian counterparts, yet they perform overlapping functions by binding and inhibiting BH3 (Bcl-2 homology 3)-motif-containing proteins. We investigated the BH3 binding properties of the herpesvirus Bcl-2 homologs K...

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Bibliographic Details
Main Authors:	Foight, Glenna W., Keating, Amy E.
Other Authors:	Massachusetts Institute of Technology. Department of Biological Engineering
Format:	Article
Language:	en_US
Published:	Elsevier 2017
Online Access:	http://hdl.handle.net/1721.1/109320 https://orcid.org/0000-0003-3749-7092 https://orcid.org/0000-0003-4074-8980

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