Engineering Yarrowia lipolytica for poly-3-hydroxybutyrate production

Strains of Yarrowia lipolytica were engineered to express the poly-3-hydroxybutyrate (PHB) biosynthetic pathway. The genes for β-ketothiolase, NADPH-dependent acetoacetyl-CoA reductase, and PHB synthase were cloned and inserted into the chromosome of Y. lipolytica. In shake flasks, the engineered st...

Full description

Bibliographic Details
Main Authors: Li, Zhengjun, Qiao, Kangjian, Liu, Nian, Stephanopoulos, Gregory
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Springer-Verlag 2017
Online Access:http://hdl.handle.net/1721.1/109321
https://orcid.org/0000-0002-1164-8692
https://orcid.org/0000-0001-6909-4568