Engineering Yarrowia lipolytica for poly-3-hydroxybutyrate production
Strains of Yarrowia lipolytica were engineered to express the poly-3-hydroxybutyrate (PHB) biosynthetic pathway. The genes for β-ketothiolase, NADPH-dependent acetoacetyl-CoA reductase, and PHB synthase were cloned and inserted into the chromosome of Y. lipolytica. In shake flasks, the engineered st...
Main Authors: | Li, Zhengjun, Qiao, Kangjian, Liu, Nian, Stephanopoulos, Gregory |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | English |
Published: |
Springer-Verlag
2017
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Online Access: | http://hdl.handle.net/1721.1/109321 https://orcid.org/0000-0002-1164-8692 https://orcid.org/0000-0001-6909-4568 |
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