Structural diversity in the AdoMet radical enzyme superfamily

AdoMet radical enzymes are involved in processes such as cofactor biosynthesis, anaerobic metabolism, and natural product biosynthesis. These enzymes utilize the reductive cleavage of S-adenosylmethionine (AdoMet) to afford l-methionine and a transient 5′-deoxyadenosyl radical, which subsequently ge...

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Bibliographic Details
Main Authors: Dowling, Daniel P., Vey, Jessica L., Croft, Anna K., Drennan, Catherine L.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2017
Online Access:http://hdl.handle.net/1721.1/109390
https://orcid.org/0000-0001-5486-2755