Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents

Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents

The following work describes the development of a novel noninvasive transmucosal drug delivery system, the chitosan sponge matrix (CSM). It is composed of cationic chitosan (CS) nanoparticles (NPs) that encapsulate cisplatin (CDDP) embedded within a polymeric mucoadhesive CS matrix. CSM is designed...

Full description

Bibliographic Details
Main Authors: Powell, Geralle, Chen, Julie, Goldberg, Manijeh Nazari, Manzi, Aaron, Aydin, Erkin, Singh, Gurtej, Khoshkenar, Payam, Birdi, Amritpreet Kaur, LaPorte, Brandon, Krauskopf, Alejandro A., Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: ASME International 2017
Online Access:http://hdl.handle.net/1721.1/109416
https://orcid.org/0000-0002-6432-1124
https://orcid.org/0000-0003-3884-8376
https://orcid.org/0000-0003-1992-6164
https://orcid.org/0000-0002-6969-4309
https://orcid.org/0000-0003-1204-7570
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/109416
https://orcid.org/0000-0002-6432-1124
https://orcid.org/0000-0003-3884-8376
https://orcid.org/0000-0003-1992-6164
https://orcid.org/0000-0002-6969-4309
https://orcid.org/0000-0003-1204-7570
https://orcid.org/0000-0003-4255-0492

Similar Items