Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning

Living-cell-based screens can facilitate lead discovery of functional therapeutics of interest. A versatile and scalable method is reported that uses dense arrays of nanowells for imparting defined patterns on monolayers of cells. It is shown that this approach can coordinate a multi-component biolo...

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Bibliographic Details
Main Authors: Ozkumur, Ayca Yalcin, Love, John C, Goods, Brittany A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/109435
https://orcid.org/0000-0003-0921-3144