A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity
CACNA1I is a candidate schizophrenia risk gene. It encodes the pore-forming human CaV3.3 α1 subunit, a subtype of voltage-gated calcium channel that contributes to T-type currents. Recently, two de novo missense variations, T797M and R1346H, of hCaV3.3 were identified in individuals with schizophren...
| Główni autorzy: | , , , , , |
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| Kolejni autorzy: | |
| Format: | Artykuł |
| Język: | en_US |
| Wydane: |
Nature Publishing Group
2017
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| Dostęp online: | http://hdl.handle.net/1721.1/109441 |