Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

Myelin-reactive T cells have been identified in patients with multiple sclerosis (MS) and healthy subjects with comparable frequencies, but the contribution of these autoreactive T cells to disease pathology remains unknown. A total of 13,324 T cell libraries generated from blood of 23 patients and...

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Bibliographic Details
Main Authors: Cao, Y., Raddassi, K., Nepom, G. T., Kwok, W. W., Goods, Brittany A., Love, John C, Hafler, David A.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/109452
https://orcid.org/0000-0003-0921-3144