Following Natures Lead: On the Construction of Membrane-Inserted Toxins in Lipid Bilayer Nanodiscs

Bacterial toxin or viral entry into the cell often requires cell surface binding and endocytosis. The endosomal acidification induces a limited unfolding/refolding and membrane insertion reaction of the soluble toxins or viral proteins into their translocation competent or membrane inserted states....

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Bibliographic Details
Main Authors: Akkaladevi, Narahari, Mukherjee, Srayanta, Katayama, Hiroo, Janowiak, Blythe, Patel, Deepa, Gogol, Edward P., Pentelute, Bradley L., John Collier, R., Fisher, Mark T.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Springer-Verlag 2017
Online Access:http://hdl.handle.net/1721.1/109504